Serveur d'exploration sur les relations entre la France et l'Australie

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Travel-Associated Illness in Older Adults (>60 y)

Identifieur interne : 005794 ( Main/Exploration ); précédent : 005793; suivant : 005795

Travel-Associated Illness in Older Adults (>60 y)

Auteurs : Philippe Gautret [France] ; Jean Gaudart [France] ; Karin Leder [Australie] ; Eli Schwartz [Israël] ; Francesco Castelli [Italie] ; POH LIAN LIM [Singapour] ; Holly Murphy [Népal] ; Jay Keystone [Canada] ; Jacob Cramer [Allemagne] ; Marc Shaw [Australie] ; Jacques Boddaert [France] ; Frank Von Sonnenburg [Allemagne] ; Philippe Parola [France]

Source :

RBID : Pascal:12-0223566

Descripteurs français

English descriptors

Abstract

Background. Older individuals represent a substantial proportion of international travelers. Because of physiological changes and the increased probability of underlying medical conditions, older travelers might be at higher risk for at least some travel-associated diseases. Methods. With the aim of describing the epidemiology of travel-associated diseases in older adults, medical data were prospectively collected on ill international travelers presenting to GeoSentinel sites from 1997 to 2009. Seven thousand thirty-four patients aged 60 years and over were identified as older travelers and were compared to 56,042 patients aged 18-45 years, who were used as the young adult reference population. Results. The proportionate morbidity of several etiological diagnoses was higher in older ill travelers compared to younger ill, including notably lower respiratory tract infections, high-altitude pulmonary edema, phlebitis and pulmonary embolism, arthropod bites, severe malaria, rickettsiosis, gastritis, peptic ulcers, esophagitis and gastroesophageal reflux disease, trauma and injuries, urinary tract infections, heart disease, and death. In contrast, acute diarrhea, upper respiratory tract infections, flu and flu-like illnesses, malaria, dengue, genital infections, sexually transmitted diseases, and schistosomiasis proportionate morbidities were lower among the older group. Conclusion. Older ill travelers are more likely to suffer from certain life-threatening diseases and would benefit from reinforcement of specific preventive measures including use of anti-thrombosis compression stockings and sufficient hydration and exercises during long-distance flights, hand hygiene, use of disposable handkerchiefs, consideration of face-masks in crowded conditions, influenza and pneumococcal vaccines, progressive acclimatization to altitude, consideration of acetazolamide, and use of repellents and mosquito nets. Antibiotics for the presumptive treatment of respiratory and urinary tract infections may be considered, as well as antacid medications. At-risk patients should be referred to a specialist for medical evaluation before departing, and optimal control of co-morbidities such as cardiovascular and chronic obstructive pulmonary diseases should be achieved, particularly for high-altitude travel.


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Le document en format XML

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<name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
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<s1>Infectious Diseases and Tropical Medicine Unit, North University Hospital, AP-HM</s1>
<s2>Marseille</s2>
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<sZ>13 aut.</sZ>
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<country>France</country>
<placeName>
<region type="region">Provence-Alpes-Côte d'Azur</region>
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<name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
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<s1>Equipe Biostatistiques, LERTIM, Faculté de Médecine</s1>
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<region type="region">Provence-Alpes-Côte d'Azur</region>
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<name sortKey="Leder, Karin" sort="Leder, Karin" uniqKey="Leder K" first="Karin" last="Leder">Karin Leder</name>
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<s1>Department of Epidemiology and Preventive Medicine, Monash University</s1>
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<country>Australie</country>
<wicri:noRegion>Victoria</wicri:noRegion>
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<affiliation wicri:level="1">
<inist:fA14 i1="04">
<s1>Victorian Infectious Disease Service, Royal Melbourne Hospital</s1>
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<wicri:noRegion>Parkville, Victoria</wicri:noRegion>
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<name sortKey="Schwartz, Eli" sort="Schwartz, Eli" uniqKey="Schwartz E" first="Eli" last="Schwartz">Eli Schwartz</name>
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<s1>Center for Geographical Medicine, Chaim Sheba Medical Center</s1>
<s2>Tel Hashomer</s2>
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<country>Israël</country>
<wicri:noRegion>Tel Hashomer</wicri:noRegion>
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<name sortKey="Castelli, Francesco" sort="Castelli, Francesco" uniqKey="Castelli F" first="Francesco" last="Castelli">Francesco Castelli</name>
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<wicri:noRegion>Brescia</wicri:noRegion>
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<name sortKey="Poh Lian Lim" sort="Poh Lian Lim" uniqKey="Poh Lian Lim" last="Poh Lian Lim">POH LIAN LIM</name>
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<s1>Department of Infectious Diseases, Tan Tock Seng Hospital</s1>
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<country>Singapour</country>
<wicri:noRegion>Singapore</wicri:noRegion>
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<name sortKey="Murphy, Holly" sort="Murphy, Holly" uniqKey="Murphy H" first="Holly" last="Murphy">Holly Murphy</name>
<affiliation wicri:level="1">
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<s1>CIWEC Clinic Travel Medicine Center</s1>
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<country>Népal</country>
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<name sortKey="Keystone, Jay" sort="Keystone, Jay" uniqKey="Keystone J" first="Jay" last="Keystone">Jay Keystone</name>
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<s1>Tropical Disease Unit, Toronto General Hospital</s1>
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<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
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<name sortKey="Cramer, Jacob" sort="Cramer, Jacob" uniqKey="Cramer J" first="Jacob" last="Cramer">Jacob Cramer</name>
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<s1>Department of Tropical Medicine and Infectious Diseases, Bernhard-Nocht-Institute for Tropical Medicine</s1>
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<s3>DEU</s3>
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<country>Allemagne</country>
<placeName>
<settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
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<name sortKey="Shaw, Marc" sort="Shaw, Marc" uniqKey="Shaw M" first="Marc" last="Shaw">Marc Shaw</name>
<affiliation wicri:level="1">
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<s1>Worldwise Travellers Health and Vaccination Centre, Auckland, New Zealand; ⁄⁄James Cook University</s1>
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<sZ>10 aut.</sZ>
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<country>Australie</country>
<wicri:noRegion>Townsville, Queensland</wicri:noRegion>
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<name sortKey="Boddaert, Jacques" sort="Boddaert, Jacques" uniqKey="Boddaert J" first="Jacques" last="Boddaert">Jacques Boddaert</name>
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</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
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<name sortKey="Von Sonnenburg, Frank" sort="Von Sonnenburg, Frank" uniqKey="Von Sonnenburg F" first="Frank" last="Von Sonnenburg">Frank Von Sonnenburg</name>
<affiliation wicri:level="4">
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<s1>Department of Infectious Diseases and Tropical Medicine, LMU University of Munich</s1>
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<country>Allemagne</country>
<placeName>
<region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
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<settlement type="city">Munich</settlement>
</placeName>
<orgName type="university">Université Louis-et-Maximilien de Munich</orgName>
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<name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
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<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
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<date when="2012">2012</date>
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<title xml:lang="en" level="a">Travel-Associated Illness in Older Adults (>60 y)</title>
<author>
<name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
<affiliation wicri:level="3">
<inist:fA14 i1="01">
<s1>Infectious Diseases and Tropical Medicine Unit, North University Hospital, AP-HM</s1>
<s2>Marseille</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
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<author>
<name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
<affiliation wicri:level="3">
<inist:fA14 i1="02">
<s1>Equipe Biostatistiques, LERTIM, Faculté de Médecine</s1>
<s2>Marseille</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
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<name sortKey="Leder, Karin" sort="Leder, Karin" uniqKey="Leder K" first="Karin" last="Leder">Karin Leder</name>
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<inist:fA14 i1="03">
<s1>Department of Epidemiology and Preventive Medicine, Monash University</s1>
<s2>Victoria</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="04">
<s1>Victorian Infectious Disease Service, Royal Melbourne Hospital</s1>
<s2>Parkville, Victoria</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Parkville, Victoria</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Schwartz, Eli" sort="Schwartz, Eli" uniqKey="Schwartz E" first="Eli" last="Schwartz">Eli Schwartz</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Center for Geographical Medicine, Chaim Sheba Medical Center</s1>
<s2>Tel Hashomer</s2>
<s3>ISR</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Israël</country>
<wicri:noRegion>Tel Hashomer</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Castelli, Francesco" sort="Castelli, Francesco" uniqKey="Castelli F" first="Francesco" last="Castelli">Francesco Castelli</name>
<affiliation wicri:level="1">
<inist:fA14 i1="06">
<s1>Institute for Infectious and Tropical Disease, University of Brescia</s1>
<s2>Brescia</s2>
<s3>ITA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Brescia</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Poh Lian Lim" sort="Poh Lian Lim" uniqKey="Poh Lian Lim" last="Poh Lian Lim">POH LIAN LIM</name>
<affiliation wicri:level="1">
<inist:fA14 i1="07">
<s1>Department of Infectious Diseases, Tan Tock Seng Hospital</s1>
<s2>Singapore</s2>
<s3>SGP</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Singapour</country>
<wicri:noRegion>Singapore</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Murphy, Holly" sort="Murphy, Holly" uniqKey="Murphy H" first="Holly" last="Murphy">Holly Murphy</name>
<affiliation wicri:level="1">
<inist:fA14 i1="08">
<s1>CIWEC Clinic Travel Medicine Center</s1>
<s2>Kathmandu</s2>
<s3>NPL</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Népal</country>
<wicri:noRegion>CIWEC Clinic Travel Medicine Center</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Keystone, Jay" sort="Keystone, Jay" uniqKey="Keystone J" first="Jay" last="Keystone">Jay Keystone</name>
<affiliation wicri:level="1">
<inist:fA14 i1="09">
<s1>Tropical Disease Unit, Toronto General Hospital</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Cramer, Jacob" sort="Cramer, Jacob" uniqKey="Cramer J" first="Jacob" last="Cramer">Jacob Cramer</name>
<affiliation wicri:level="3">
<inist:fA14 i1="10">
<s1>Department of Tropical Medicine and Infectious Diseases, Bernhard-Nocht-Institute for Tropical Medicine</s1>
<s2>Hamburg</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName>
<settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Shaw, Marc" sort="Shaw, Marc" uniqKey="Shaw M" first="Marc" last="Shaw">Marc Shaw</name>
<affiliation wicri:level="1">
<inist:fA14 i1="11">
<s1>Worldwise Travellers Health and Vaccination Centre, Auckland, New Zealand; ⁄⁄James Cook University</s1>
<s2>Townsville, Queensland</s2>
<s3>AUS</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Townsville, Queensland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Boddaert, Jacques" sort="Boddaert, Jacques" uniqKey="Boddaert J" first="Jacques" last="Boddaert">Jacques Boddaert</name>
<affiliation wicri:level="3">
<inist:fA14 i1="12">
<s1>Geriatric Department and Emergency Department, Inserm U-970, Pitié-Salpêtrière University Hospital, AP-HP</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Von Sonnenburg, Frank" sort="Von Sonnenburg, Frank" uniqKey="Von Sonnenburg F" first="Frank" last="Von Sonnenburg">Frank Von Sonnenburg</name>
<affiliation wicri:level="4">
<inist:fA14 i1="13">
<s1>Department of Infectious Diseases and Tropical Medicine, LMU University of Munich</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName>
<region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
<settlement type="city">Munich</settlement>
</placeName>
<orgName type="university">Université Louis-et-Maximilien de Munich</orgName>
</affiliation>
</author>
<author>
<name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
<affiliation wicri:level="3">
<inist:fA14 i1="01">
<s1>Infectious Diseases and Tropical Medicine Unit, North University Hospital, AP-HM</s1>
<s2>Marseille</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Journal of travel medicine</title>
<title level="j" type="abbreviated">J. travel med.</title>
<idno type="ISSN">1195-1982</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">Journal of travel medicine</title>
<title level="j" type="abbreviated">J. travel med.</title>
<idno type="ISSN">1195-1982</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Travel</term>
<term>Tropical medicine</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Voyage</term>
<term>Adulte</term>
<term>Médecine tropicale</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Voyage</term>
<term>Adulte</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Background. Older individuals represent a substantial proportion of international travelers. Because of physiological changes and the increased probability of underlying medical conditions, older travelers might be at higher risk for at least some travel-associated diseases. Methods. With the aim of describing the epidemiology of travel-associated diseases in older adults, medical data were prospectively collected on ill international travelers presenting to GeoSentinel sites from 1997 to 2009. Seven thousand thirty-four patients aged 60 years and over were identified as older travelers and were compared to 56,042 patients aged 18-45 years, who were used as the young adult reference population. Results. The proportionate morbidity of several etiological diagnoses was higher in older ill travelers compared to younger ill, including notably lower respiratory tract infections, high-altitude pulmonary edema, phlebitis and pulmonary embolism, arthropod bites, severe malaria, rickettsiosis, gastritis, peptic ulcers, esophagitis and gastroesophageal reflux disease, trauma and injuries, urinary tract infections, heart disease, and death. In contrast, acute diarrhea, upper respiratory tract infections, flu and flu-like illnesses, malaria, dengue, genital infections, sexually transmitted diseases, and schistosomiasis proportionate morbidities were lower among the older group. Conclusion. Older ill travelers are more likely to suffer from certain life-threatening diseases and would benefit from reinforcement of specific preventive measures including use of anti-thrombosis compression stockings and sufficient hydration and exercises during long-distance flights, hand hygiene, use of disposable handkerchiefs, consideration of face-masks in crowded conditions, influenza and pneumococcal vaccines, progressive acclimatization to altitude, consideration of acetazolamide, and use of repellents and mosquito nets. Antibiotics for the presumptive treatment of respiratory and urinary tract infections may be considered, as well as antacid medications. At-risk patients should be referred to a specialist for medical evaluation before departing, and optimal control of co-morbidities such as cardiovascular and chronic obstructive pulmonary diseases should be achieved, particularly for high-altitude travel.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Allemagne</li>
<li>Australie</li>
<li>Canada</li>
<li>France</li>
<li>Israël</li>
<li>Italie</li>
<li>Népal</li>
<li>Singapour</li>
</country>
<region>
<li>Bavière</li>
<li>District de Haute-Bavière</li>
<li>Hambourg</li>
<li>Provence-Alpes-Côte d'Azur</li>
<li>Île-de-France</li>
</region>
<settlement>
<li>Hambourg</li>
<li>Marseille</li>
<li>Munich</li>
<li>Paris</li>
</settlement>
<orgName>
<li>Université Louis-et-Maximilien de Munich</li>
</orgName>
</list>
<tree>
<country name="France">
<region name="Provence-Alpes-Côte d'Azur">
<name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
</region>
<name sortKey="Boddaert, Jacques" sort="Boddaert, Jacques" uniqKey="Boddaert J" first="Jacques" last="Boddaert">Jacques Boddaert</name>
<name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
<name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
</country>
<country name="Australie">
<noRegion>
<name sortKey="Leder, Karin" sort="Leder, Karin" uniqKey="Leder K" first="Karin" last="Leder">Karin Leder</name>
</noRegion>
<name sortKey="Leder, Karin" sort="Leder, Karin" uniqKey="Leder K" first="Karin" last="Leder">Karin Leder</name>
<name sortKey="Shaw, Marc" sort="Shaw, Marc" uniqKey="Shaw M" first="Marc" last="Shaw">Marc Shaw</name>
</country>
<country name="Israël">
<noRegion>
<name sortKey="Schwartz, Eli" sort="Schwartz, Eli" uniqKey="Schwartz E" first="Eli" last="Schwartz">Eli Schwartz</name>
</noRegion>
</country>
<country name="Italie">
<noRegion>
<name sortKey="Castelli, Francesco" sort="Castelli, Francesco" uniqKey="Castelli F" first="Francesco" last="Castelli">Francesco Castelli</name>
</noRegion>
</country>
<country name="Singapour">
<noRegion>
<name sortKey="Poh Lian Lim" sort="Poh Lian Lim" uniqKey="Poh Lian Lim" last="Poh Lian Lim">POH LIAN LIM</name>
</noRegion>
</country>
<country name="Népal">
<noRegion>
<name sortKey="Murphy, Holly" sort="Murphy, Holly" uniqKey="Murphy H" first="Holly" last="Murphy">Holly Murphy</name>
</noRegion>
</country>
<country name="Canada">
<noRegion>
<name sortKey="Keystone, Jay" sort="Keystone, Jay" uniqKey="Keystone J" first="Jay" last="Keystone">Jay Keystone</name>
</noRegion>
</country>
<country name="Allemagne">
<region name="Hambourg">
<name sortKey="Cramer, Jacob" sort="Cramer, Jacob" uniqKey="Cramer J" first="Jacob" last="Cramer">Jacob Cramer</name>
</region>
<name sortKey="Von Sonnenburg, Frank" sort="Von Sonnenburg, Frank" uniqKey="Von Sonnenburg F" first="Frank" last="Von Sonnenburg">Frank Von Sonnenburg</name>
</country>
</tree>
</affiliations>
</record>

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